D-Dimer is the simplest degradation product of fibrin, and the increase in its mass concentration reflects the hypercoagulable state and secondary fibrinolysis in the body. Therefore, the mass concentration of D-Dimer is of great significance for the diagnosis, efficacy evaluation, and prognosis judgment of thrombotic diseases.
In clinical settings such as deep vein thrombosis (DVT), pulmonary embolism (PE), and diffuse intravascular coagulation (DIC), elevated D-dimer concentrations can be observed. D-Dimer levels also increase during normal pregnancy, but excessive levels are associated with complications.